Ketamine for the treatment of addiction: Evidence and potential mechanisms

Highlights Preliminary evidence suggests that ketamine may be effective in addiction. Potential interacting mechanisms are enhancing neurogenesis and psychological therapies. Ketamine may reduce depressive symptoms in a risky window for addiction relapse. Abstract Ketamine is a dissociative anaesthetic drug which acts on the central nervous system chiefly through antagonism of the n-methyl-d-aspartate (NMDA) receptor. Recently, ketamine has attracted attention as a rapid-acting anti-depressant but other studies have also …

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Quantifying the Cost of Depression

Key Findings Approximately 6-7% of full-time U.S. workers experienced major depression (MDD) within the past year. The total economic burden of MDD is now estimated to be $210.5 billion per year. For every dollar spent on MDD direct costs in 2010, an additional $1.90 was spent on MDD-related indirect costs. An important study reveals just …

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Why Is Ketamine Infusion Therapy So Effective?

Before we discuss why ketamine infusion therapy is so effective, first let’s take a step back and look at what it is. Ketamine is an FDA-approved drug that has been used by the medical community in the United States since the 1970s. It is commonly used as an aesthetic drug during surgical procedures and as …

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Ketamine Infusion Treatment: Is It Right For You?

Meet Lara. She’s in her thirties, she’s educated, and she has a secure position at a reputable company where she makes good money. But she isn’t happy. In fact, though she might be successful by society’s’ standards, she has struggled with depression for years. She has tried focusing on her career more and this hasn’t …

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Ketamine’s antidepressive effects tied to opioid system in brain

Ketamine’s antidepressive effects require activation of opioid receptors in the brain, a new Stanford study shows. The surprising finding may alter how new antidepressants are developed and administered in order to mitigate the risk of opioid dependence. Scientists at the Stanford University School of Medicine have discovered that ketamine works as an antidepressant at least in part …

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Boys rescued from Thai cave were sedated with ketamine

Medics who treated the 12 boys and their soccer coach rescued from a cave in Thailand last year credit the drug ketamine with playing a key role in the daring and dangerous mission to extract them. According to details of the rescue released in a medical journal Thursday, the boys were given unspecified doses of ketamine by …

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Getting the Inside Dope on Ketamine’s Mysterious Ability to Rapidly Relieve Depression

From Scientific American Ketamine has been called the biggest thing to happen to psychiatry in 50 years, due to its uniquely rapid and sustained antidepressant effects. It improves symptoms in as little as 30 minutes, compared with weeks or even months for existing antidepressants, and is effective even for the roughly one third of patients with so-called …

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Could Ketamine Be A Treatment for Depression?

From RollingStone.com Anne McNealis tried at least a dozen medications to manage her depression before turning to ketamine. Prozac, Paxil, Zoloft, Cymbalta – you name it, she’s used it. But McNealis couldn’t tolerate those conventional treatments, she says. She has struggled with severe depression for about 20 years and even on medication, she still woke …

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How New Ketamine Drug Helps with Depression

On March 5, 2019 the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made waves for its surprising antidepressant effect. Interestingly, studies from Yale research labs showed that the drug ketamine, which was widely used as …

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Bespoke Treatment focuses on non-medication treatments that work. We are the first boutique center in Southern California to specialize in personalized TMS therapy, Ketamine treatment, and psychiatry.

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