Find Quick Relief with Ketamine Therapy

Low-dose ketamine in a comfortable, controlled clinical setting brings profound depression symptom relief faster than SSRIs. Some patients report feeling better as soon as their first session. Schedule your ketamine treatment in Las Vegas, Santa Monica, and Los Angeles today.

Get Started

Ketamine Treatment: A Proven Alternative to SSRIs

Searching for relief from depression, anxiety, and trauma can be a long and exhausting journey–particularly when you’ve tried multiple ways to cure your depression, aren’t able to manage anxiety, or have struggled with how to overcome trauma. Finding the right therapist for you can be difficult, too. Most anti-depressants often take trial and error, weeks to work, and can have unwelcome side effects.

If you’ve found that talk therapy and SSRIs don’t work for you, don’t give up hope. Consider ketamine treatment. Many of our patients find relief within a few sessions, even as soon as the first session.

What is Ketamine?

Ketamine is a medication that has been widely used for over 50 years. It was originally developed as a pediatric anesthetic to help young patients feel no pain during surgeries and medical procedures. Today, smaller doses are also used by mental health professionals to treat certain mental health conditions–like trauma, depression, and anxiety.

What is Ketamine Therapy?

Ketamine has shown significant promise in treating depression, anxiety, trauma, post-traumatic stress disorder (PTSD), and even chronic pain. Ketamine therapy is a safe, well-tolerated treatment option when prescribed and administered by a mental health professional in a controlled, therapeutic setting.
Ketamine therapy can include ketamine infusions, ketamine injections, ketamine lozenges, or ketamine troches.

“Ketamine, given intravenously, might be the most important breakthrough in antidepressant treatment in decades.”

– Thomas Insel
former Director of the National Institute for Mental Health

How Does Ketamine Treatment Work?

Ketamine can be used to treat anxiety and depression. But is ketamine an antidepressant? Not in the conventional sense. Ketamine has psychedelic properties and works differently in your brain compared to traditional antidepressant medications.

Traditional antidepressants, like SSRIs, have to build up in your system in order to change your brain chemistry. In contrast, ketamine’s mood-boosting effects take place almost immediately.

How Ketamine Works 

Ketamine affects a specific chemical in the brain: glutamate. Glutamate plays a key role in both mood regulation and pain perception. By modulating glutamate, ketamine—among other psychedelic medications—can quickly reduce symptoms of depression, anxiety, and trauma. Ketamine had rapid effects on mood, often providing relief within just hours or days.

“Just one infusion had the benefits of 1,000 therapy sessions.”

– Bespoke Treatment Patient

Our Ketamine Treatment Options

Bespoke Treatment offers many ketamine treatment options in Los Angeles, Santa Monica, and Las Vegas– all administered by trained and experienced psychiatric mental health professionals.

 Ketamine Infusions

A slow, constant IV ketamine drip is delivered directly into your bloodstream to achieve the highest bioavailability possible. A brief series of infusions can provide deep experiences with lasting effects for reductions in depression, anxiety, and PTSD.

Learn More

At-Home Ketamine Assisted Therapy

Low-dose ketamine has the ability to break down barriers and promote breakthroughs in conjunction with psychotherapy—all in the comfort of your own home under the virtual guidance of our clinicians. In addition, as part of our holistic Intensive Outpatient Program, you’ll have access to specially trained therapists and exclusive integration sessions.

Learn More

Spravato Esketamine Nasal Spray

Spravato is the only FDA-approved form of ketamine. This in-clinic option is covered by most insurance and can provide rapid relief for treatment-resistant depression.

Learn More

What Does Ketamine Treat?


For those who are searching for answers to how to help treatment-resistant depression, ketamine may be the answer. Ketamine provides fast-acting effects for a number of depression subtypes. We can address various types of depression with ketamine therapy including: Major Depressive Disorder, Persistent Depressive Disorder, Postpartum Depression (if not breastfeeding), and more.


Trauma centers offer ketamine because trauma, including PTSD and C-PTSD, doesn’t typically respond to traditional psychiatric medications. So, how does ketamine help with trauma? Due to the psychedelic and the neuroplasticity inducing nature of ketamine, people with trauma often gain closure and new perspectives on past traumatic events. Ketamine can help trauma patients and those living with PTSD gain quick relief: and move forward with hope and clarity—particularly when ketamine is paired with psychotherapy.

Bespoke Treatment proudly works with trauma survivors of all kinds, including Veterans.


Anxiety can be overwhelming both mentally and physically. Ketamine therapy for anxiety is a wonderful tool for those who have found that their anxiety symptoms are debilitating–particularly where common approaches like medication and therapy haven’t worked.

Ketamine treatment for anxiety can be used in cases of General Anxiety Disorder, Panic Disorder, PTSD, OCD, and more. Ketamine can provide immediate benefits for anxiety symptoms–and result in long-term positive changes.

The Science Behind Ketamine

Ketamine works differently and more quickly than traditional SSRIs. We know that ketamine is effective in treating mental health disorders like depression, PTSD, trauma, and anxiety. However, researchers are still trying to pinpoint the exact mechanism behind ketamine’s efficacy.

Here’s the latest in developing understanding behind why ketamine works for mood disorders.

Ketamine Increases Glutamate Release

When administered in low doses, ketamine produces a surge in glutamate. Glutamate encourages the growth of the brain’s synapses. Increased glutamate helps to quickly strengthen, stimulate, and restore the neural connections in the regions of the brain that are affected by depression. These strengthened neurons, previously stifled by depression, improve brain circuit function.

Ketamine Opens Critical Periods

Researchers have also identified changes with ketamine treatments related to increases in neuroplasticity and the opening of critical periods. Critical periods are physiologically special times when the brain is especially open to learning and adapting to new information. When critical periods open up due to ketamine administration, it sets a cascade of neurotransmitters and other cells to rapidly adapt to new, healthier habits and coping mechanisms. For example, psychotherapy during a ketamine-induced critical period (also referred to as ketamine assisted psychotherapy) is thought to be much more effective than psychotherapy during a closed critical period.

Ketamine Treatment: What to Expect from the Process

Before Your Treatment

Your Initial Consultation

During your initial consultation, your provider will meet with you to complete a comprehensive mental and physical health exam. We’ll go over your full health history–including your current mental health symptoms, health conditions, and medications before determining if ketamine is right for you.

Dress Comfortably

On the day of your treatment, you should wear clothing that makes you feel comfortable and relaxed.

Schedule Your Ride

We require that anyone receiving a ketamine treatment does not drive to or from their appointment. Ketamine can cause short-term side effects immediately after treatment, including increased sleepiness or headaches—these symptoms resolve by the next day. We recommend having a trusted friend or family member take you to and from treatment–ridesharing services like Uber or Lyft are also excellent options.

During Your Treatment

A Comfortable Environment

Our ketamine treatment rooms are private and comfortable–expect soft lighting, comfortable

Close Monitoring

During ketamine treatment, your provider will monitor you closely while you rest in a comfortable, private room. Some people prefer to have providers check in periodically, preferring to be alone for most of the experience, while others enjoy having our clinicians with them the entire time.

Profound Relief and Mild Psychedelic Effects

During treatment, many patients feel relaxed and are able to get in touch with their innermost thoughts to gain new perspectives on past emotional experiences–both positive and negative. Many patients find healing through newfound closure, clarity, and perspectives during ketamine treatment.

Some patients may experience mild side effects during treatment. Ketamine therapy side effects can include feeling detached from your surroundings, floating sensations, or experiencing vivid dreams. These effects are temporary and usually wear off quickly after your treatment.

 What to Expect After Ketamine Treatment

Feeling Sleepy or a Short-Term Mild Headache 

Feeling mildly sedated or having a headache is normal after a session. Patients are not allowed to drive themselves home after receiving ketamine treatments.

Increased Feelings of Relief

Many patients begin to feel relief from acute and chronic symptoms immediately after their first session, although they often need to complete their series for continued benefits.

Beyond symptom relief, patient experiences and takeaways vary–even session to session. However, our patients commonly report long-term feelings of: interconnectedness, newfound vigor for life, acceptance around past negative experiences, clarity of future decisions and life goals, and an increased feeling of sense of self.

Find Relief with Ketamine Therapy at Bespoke Treatment

If you reside in Los Angeles, Las Vegas, and Santa Monica and are searching for “ketamine treatment near me”, Bespoke Treatment is the right place for you. Contact our mental health clinic and let your mind heal.

Get Started

Frequently Asked Questions

Yes, we accept insurance!

(833) 867-2329

Get Help Today!

Contact Us