Ketamine: The Evolution from Battlefield Anesthesia to Groundbreaking Infusion Treatment

Medical Reviewer: Nima A. Fahimian, MD

Author:

Ben Spielberg, M.S., Ph.D. Candidate

Published:

[While the use of ketamine for medicinal purposes isn’t new (in fact, it’s been implemented for nearly fifty years for a variety of uses), there’s been an uprise in utilizing intravenous treatments over the past two decades. Medical professionals are implementing it in emergency room settings, as well as in their clinics, for the management of chronic pain, depression, PTSD, and a host of other treatments.

What Is the History of Ketamine in Medicine?

Ketamine came to fruition in the early 1960s, when Parke Davis researchers were searching for a derivative of phencyclidine that could help limit the compounds for unmanageable side effects. In 1964, following successful animal testing, ketamine was administered to the researchers’ first human subject. The results demonstrated remarkable anesthetic results. While this drug was initially approved for use in veterinary settings, it was officially passed by the FDA in 1970 for short-term anesthetic use in humans. And, on the Vietnam battlefield, this soon became extremely useful. In the early 1970s, John C. Lily tested whether taking ketamine could soften his migraines, after his attempts to do so with LSD failed. It wasn’t until it was introduced to him by a physician friend of his that he became convinced of its effectivity and began using it in his research. Russian researchers, specifically Evgeny Krupitsky, used ketamine between 1985 and 1995, in what they referred to as Ketamine Psychedelic Therapy. Krupitsky and his team worked at the Leningrad Regional Center for Alcoholism and Drug Addiction Therapy, administering ketamine to over 1,000 patients with alcoholism and other chemical dependencies. They published a report in 1997 that indicated that ketamine therapy brought on no significant side effects. Yale University then got on the bandwagon and began its research on ketamine during the mid-1990s. Even though the FDA wasn’t approving anything from pharmaceutical companies because, by this time, ketamine was found unprofitable, researchers kept looking into how it could be used for depression. Eventually, the FDA did approve ketamine for depression treatment, and it continues to be prescribed “off-label” by many practices. There’s growing research for trials and real-world applications of ketamine use for psychiatric conditions. These conditions include anxiety, bipolar disorder, major depressive disorder, OCD, and PTSD.

People We Have Helped

How Is Ketamine Being Used Now?

Many are turning to ketamine as an alternative therapy drug. Some of these individuals may have been on medications for an extended period and are seeking an alternative; others may have made attempts at taking medications but were not responsive to conventional methods. Because ketamine is such a versatile drug, it’s possible for medical professionals to use it for more than treating depression or as an anesthetic. Throughout the Los Angeles area, we’re seeing physicians using Ketamine Infusion Therapy to help patients with chronic pain management. Ketamine is also used by these doctors to treat acute pain. If patients don’t respond to traditional medications, they can likely benefit the most from ketamine therapy. Ketamine is also used to help those who are seeking an alternative for opioid medications, as well as for those who are attempting to reduce their dependency. In doing so, it’s possible to use ketamine to help those who are addicted to stop or reduce their usage of opioids. And, while undergoing ketamine therapy, they’ll experience little to no side effects. Since the mid-’90s, physicians have found ketamine to be useful for relieving short-term pain. It’s also an effective way of treating many types of chronic pain, including burns, migraines, and fibromyalgia. Psychiatrists and physicians also trust ketamine as a way of treating those who have psychiatric disorders or pain. Patients receive these infusions while under close medical supervision, to ensure that correct dosing and minimal side effects occur.

How Can Bespoke Treatment Clinics in Los Angeles Help You?

Helping those suffering from chronic pain, depression, suicidal tendencies, bipolar disorder, PTSD, OCD, anxiety, and more, Dr. Nima Fahimian, MD, of Bespoke Treatment works diligently as one of the leading providers of ketamine infusion therapy. Make an appointment with Dr. Ben Spielberg team to learn more about how ketamine can help you.

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Reviews

As someone who has struggled with depression for years, I was skeptical about trying alternative treatment options. However, the team at Bespoke Treatment made me feel comfortable and supported throughout the entire process. Not only did their TMS therapy provide significant relief for my depression symptoms, but I also had a positive experience with their ketamine therapy. The staff was incredibly knowledgeable and took the time to answer all of my questions and address any concerns I had.

I can't recommend this place enough. I had an incredible experience with the treatment I received here. From the administrative staff to the medical team, I really appreciated the outstanding care and attention I received and always felt listened to. There was never any sense of rushing or a "one size fits all" approach, which is sadly very much the norm elsewhere. I highly recommend coming here for the excellent quality of services, professionalism, and warmth that are so important when you're needing mental health treatment.

TMS was amazing for me . I loved my treatments , the doctors, the staff as well as the office itself. Its an amazing place to go for your wellbeing . Everyone is super nice, kind and extremely professional. The place is very easy to get to with available parking. Basically no stress. I felt very comfortable with my technician and all his knowledge about TMS . I also loved Dr. Fahimian . He is extremely educated and knowable in his field. His patience in taking his time to answer all my questions and concerns were highly appreciated.

I was severely depressed when starting treatment. I could not handle meds and had big hopes that TMS would work. It absolutely did wonders for lifting my depression. I have my life back. I have motivation to do things and energy to achieve goals. I really wasn’t sure if the TMS method would work, but it did and I am forever grateful. It even helped with my ruminating thoughts. I’m able to be in the moment and get back into doing things I enjoy. I highly recommend TMS to anyone who needs it.

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