How Long Does Ketamine Pain Relief Last

Medical Reviewer: Nima A. Fahimian, MD

Author:

Ben Spielberg, M.S., Ph.D. Candidate

Published:

If you have been dealing with chronic pain, you know how challenging it can be to achieve lasting relief. Most standard pain-relief treatments only offer temporary respite, leaving you trapped in the same cycle of discomfort and distress for months or even years.

What is Ketamine?

If you have been looking into alternative treatments for chronic pain, you may have come across ketamine. Ketamine has been used during surgeries for many years to provide analgesia for acute pain. Recently, ketamine has also been effective in treating chronic pain and mental health conditions such as anxiety, depression, and PTSD.

Before starting their ketamine therapy at Bespoke Treatment clinics, our clients often ask, “How long will the effects actually last? Will ketamine provide a lasting relief, or will the pain come right back? And what if it doesn’t work for me?” Since ketamine doesn’t offer a one-size-fits-all solution, having someone to answer your questions about how long ketamine pain relief lasts can help set realistic expectations.

What Happens During a Ketamine Treatment Plan

Ketamine works by targeting the brain’s NMDA receptors. NMDA is a neurotransmitter that plays a role in signaling pain. Ketamine can reduce or stop chronic pain by blocking NMDA receptors, which calms nerve activity and reduces pain signals. Ketamine has shown promise in bringing long-term pain relief to patients with chronic pain conditions such as fibromyalgia, migraines, and cluster headaches.

How Long Can You Expect the Effects of Ketamine Treatment to Last?

At the Bespoke Treatment clinics in California, ketamine treatment involves ketamine IV infusions.

Ketamine Infusions

Ketamine infusions usually begin with a series of doses over a short period, typically eight IV ketamine infusions over four weeks. Many patients experience pain relief shortly after this time. However, the duration of relief can be highly variable. After the initial treatment, some people experience weeks or months of reduced pain. Others require maintenance treatments every few weeks to sustain the effects. Long-term relief typically depends on both your individual biology and the cause of the pain.

How Does Dosage Impact the Results of Ketamine?

The dosage of ketamine you receive plays a big role in how quickly and how long you feel the benefits. At Bespoke Treatment, we don’t believe in a “one-size-fits-all” approach. Instead, we personalize your dose to you. Higher doses don’t always mean longer relief and may increase the risk of side effects. In chronic pain, long-term treatment planning is crucial, so we make sure to customize the dosage based on your symptoms, treatment background, and the response of your body.

How Ketamine Affects Your Body

Ketamine doesn’t just improve your mood. It literally rewires your brain and body. It helps relieve pain by attaching to NMDA receptors in the brain and boosting a chemical called glutamate. Glutamate helps your brain rewire itself and can “reset” how your nervous system processes pain, making your brain less sensitive to pain signals.

Moreover, ketamine can help regulate weight, improve sleep, and lower stress levels by calming your nervous system. Most patients report feeling more relaxed, having more clarity, and being more capable of managing everyday life upon treatment.

Coexisting Medical Conditions That May Affect Pain Relief Outcomes

If you have coexisting conditions like autoimmune disorders or mental health issues, these can affect how well ketamine works and for how long. Individuals with treatment-resistant pain disorders often need more frequent or longer-term treatment regimens. Your overall health, sleep, nutrition, and stress levels can also play a role. That’s why a holistic, individualized approach will typically give you the best results.

Final Thoughts

Typically, the pain relief from a single dose of ketamine lasts for a few days to a few weeks. With repeated doses, the effects can be long-lasting. Some patients experience months of reduced pain following a full series, especially when used in combination with other therapies like physical rehabilitation, psychotherapy, or lifestyle modification. Working with a knowledgeable provider and being open to ongoing adjustments can help you get the most from your treatment.

If you or someone you love is suffering from chronic pain, Bespoke Treatment can help. Book an appointment today and learn if ketamine therapy is the right option for you. Contact us today to find out more.

Reviews

As someone who has struggled with depression for years, I was skeptical about trying alternative treatment options. However, the team at Bespoke Treatment made me feel comfortable and supported throughout the entire process. Not only did their TMS therapy provide significant relief for my depression symptoms, but I also had a positive experience with their ketamine therapy. The staff was incredibly knowledgeable and took the time to answer all of my questions and address any concerns I had.

I can't recommend this place enough. I had an incredible experience with the treatment I received here. From the administrative staff to the medical team, I really appreciated the outstanding care and attention I received and always felt listened to. There was never any sense of rushing or a "one size fits all" approach, which is sadly very much the norm elsewhere. I highly recommend coming here for the excellent quality of services, professionalism, and warmth that are so important when you're needing mental health treatment.

TMS was amazing for me . I loved my treatments , the doctors, the staff as well as the office itself. Its an amazing place to go for your wellbeing . Everyone is super nice, kind and extremely professional. The place is very easy to get to with available parking. Basically no stress. I felt very comfortable with my technician and all his knowledge about TMS . I also loved Dr. Fahimian . He is extremely educated and knowable in his field. His patience in taking his time to answer all my questions and concerns were highly appreciated.

I was severely depressed when starting treatment. I could not handle meds and had big hopes that TMS would work. It absolutely did wonders for lifting my depression. I have my life back. I have motivation to do things and energy to achieve goals. I really wasn’t sure if the TMS method would work, but it did and I am forever grateful. It even helped with my ruminating thoughts. I’m able to be in the moment and get back into doing things I enjoy. I highly recommend TMS to anyone who needs it.

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