What Is The Success Rate of TMS Therapy?

Medical Reviewer: Nima A. Fahimian, MD

Author:

Ben Spielberg, M.S., Ph.D. Candidate

Published:

If you’re looking for relief from your depression symptoms, you may be exhausting all options. One of those that could help may be transcranial magnetic stimulation. Transcranial Magnetic Stimulation (TMS) is a non-invasive medical procedure that uses magnetic fields to stimulate nerve cells in the brain. It’s primarily used to treat certain mental health conditions, such as major depressive disorder and some anxiety disorders, when other treatments have proven to be ineffective. The success rates of transcranial magnetic stimulation (TMS) typically fall within the range of 70% to 80%, indicating that a significant majority of individuals experience substantial relief post-treatment. Remarkably, approximately 50% of individuals achieve full remission, signifying the absence of depressive symptoms following only a single treatment regimen.

To fully understand the effectiveness of TMS, it is crucial to juxtapose it with the effectiveness of medications such as SSRIs. SSRIs or Selective Serotonin Reuptake Inhibitors are a class of commonly prescribed antidepressant medications. While they can be effective in treating depression and anxiety disorders, they can also come with potential side effects.

The STAR*D study, a substantial clinical investigation backed by the NIMH, revealed that frequently prescribed medications, like Selective Serotonin Reuptake Inhibitors (SSRIs), exhibit a mere 27.5% success rate. Notably, this success rate declines further when a particular SSRI prove ineffective, which is prevalent in most cases of treatment-resistant depression, another form of medication has less chances of being successful. As an individual progresses through four medication attempts, the likelihood of succeeding with the subsequent medication dwindles to less than 7%. It’s worth noting that the evaluation period for determining the success of a specific antidepressant through medication trials can span 1-2 months. Consequently, individuals often invest roughly 4-8 months experimenting with different antidepressant medications, even though the prospect of achieving remission is exceedingly low. Additionally, this extended use of medications escalates the risk of encountering adverse side effects such as:

  • Sexual dysfunction
  • Gastrointestinal issues and discomfort
  • Nausea
  • Increased appetite, weight gain, or weight changes
  • Sleep disturbances, either insomnia (insufficient sleep) or hypersomnia (excessive sleep)
  • Anxiety or restlessness
  • Drowsiness
  • Excessive sweating
  • Agitation and/or irritability
  • Headaches
  • Increased risk of bleeding

This context exposes the necessity for alternative solutions for individuals living with treatment-resistant depression. While electroconvulsive therapy (ECT) was thought to be the gold standard, it only has an average of a 48% remission rate in those experiencing treatment resistant depression. In addition, ECT has a long list of adverse side effects and is exponentially more invasive when compared to TMS.

Early clinical investigations involving TMS were particularly focused on a particular demographic, characterized by a notably low probability of achieving remission. Surprisingly, two-thirds of these patients experienced positive outcomes post-TMS, a revelation that defied expectations. Notably, individuals who had previously battled hopelessness, endured anhedonia, and exhausted all available options discovered relief from their symptoms in only a span of six weeks.

In mid-2020, we conducted an independent research initiative, yielding success rates significantly surpassing the initially reported figures. This disparity could potentially be attributed to our specialization in both theta burst stimulation and a tailored TMS approach. At Bespoke Treatment centers we believe that each brain possesses it’s own unique characteristics, rendering a standardized one-size-fits-all Transcranial Magnetic Stimulation protocol ineffective. As per our most recent assessment, our success rate stands impressively at 92.5%.

For those actively seeking an effective depression treatment that works, we encourage you to connect with us today at to inquire about TMS therapy in Los Angeles. Embark on a journey to discover how you can transform your life through our transformative approaches and finally overcome your symptoms of depression.

Reviews

As someone who has struggled with depression for years, I was skeptical about trying alternative treatment options. However, the team at Bespoke Treatment made me feel comfortable and supported throughout the entire process. Not only did their TMS therapy provide significant relief for my depression symptoms, but I also had a positive experience with their ketamine therapy. The staff was incredibly knowledgeable and took the time to answer all of my questions and address any concerns I had.

I can't recommend this place enough. I had an incredible experience with the treatment I received here. From the administrative staff to the medical team, I really appreciated the outstanding care and attention I received and always felt listened to. There was never any sense of rushing or a "one size fits all" approach, which is sadly very much the norm elsewhere. I highly recommend coming here for the excellent quality of services, professionalism, and warmth that are so important when you're needing mental health treatment.

TMS was amazing for me . I loved my treatments , the doctors, the staff as well as the office itself. Its an amazing place to go for your wellbeing . Everyone is super nice, kind and extremely professional. The place is very easy to get to with available parking. Basically no stress. I felt very comfortable with my technician and all his knowledge about TMS . I also loved Dr. Fahimian . He is extremely educated and knowable in his field. His patience in taking his time to answer all my questions and concerns were highly appreciated.

I was severely depressed when starting treatment. I could not handle meds and had big hopes that TMS would work. It absolutely did wonders for lifting my depression. I have my life back. I have motivation to do things and energy to achieve goals. I really wasn’t sure if the TMS method would work, but it did and I am forever grateful. It even helped with my ruminating thoughts. I’m able to be in the moment and get back into doing things I enjoy. I highly recommend TMS to anyone who needs it.

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