Population scale data reveals the antidepressant effects of ketamine

Abstract Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of eight million reports from the FDA Adverse Effect Reporting System. The results of the examination of population scale …

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Experimental drug shows promise for treatment of postpartum depression

An experimental drug touted as a breakthrough for treating severe postpartum depression is showing some promising results in a small clinical trial. Sage Therapeutics (SAGE), based in Cambridge, Mass., reported on Tuesday that 7 of the 10 women who took the drug in the trial experienced significant improvement in their depression within 60 hours of …

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A Comprehensive Look at How Ketamine Treats Depression

Searching for Ketamine for Depression in Los Angeles? Do you believe you may be suffering from depression? If so, questions regarding receiving a diagnosis and treatments may also be on your mind. While the symptoms of depression aren’t always apparent, that doesn’t mean they aren’t real. Feelings of sadness and hopeless, as well as rage …

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If You Are Fighting Depression, Consider Ketamine

Ketamine is a drug that is completely unique, and when it comes to treating depression, the results have been so good, it’s shocked many in psychiatry. “This is a game-changer,” Dr. John Krystal, chief psychiatrist at Yale Medicine, told Medical Xpress. “When you take ketamine, it triggers reactions in your cortex that enable brain connections …

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Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial

‘- Jerome H Taylor, Angeli Landeros-Weisenberger, Catherine Coughlin, Jilian Mulqueen, Jessica A Johnson, Daniel Gabriel, Margot O Reed, Ewgeni Jakubovski and Michael H Bloch Abstract Many patients with social anxiety disorder (SAD) experience inadequate symptom relief from available treatments. Ketamine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with a potentially novel mechanism of action for the …

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How much ketamine is the right dosage for Treatment Resistant Depression?

Abstract Numerous placebo-controlled studies have demonstrated the ability of ketamine, an NMDA receptor antagonist, to induce rapid (within hours), transient antidepressant effects when administered intravenously (IV) at subanesthetic doses (0.5 mg/kg over 40 min). However, the optimal antidepressant dose remains unknown. We aimed to compare to active placebo the rapid acting antidepressant properties of a …

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Quantifying the Cost of Depression

Key Findings Approximately 6-7% of full-time U.S. workers experienced major depression (MDD) within the past year. The total economic burden of MDD is now estimated to be $210.5 billion per year. For every dollar spent on MDD direct costs in 2010, an additional $1.90 was spent on MDD-related indirect costs. An important study reveals just …

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New Hope for Depression – Time Magazine Cover Story

At last count, about 12% of Americans took antidepressants. Global revenue for antidepressants was about $14.5 billion in 2014 and is projected to grow to nearly $17 billion over the next three years. Clinical depression affects 6.7% of U.S. adults, or about 16 million people, and a growing number of children and teenagers too. It’s …

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Getting the Inside Dope on Ketamine’s Mysterious Ability to Rapidly Relieve Depression

From Scientific American Ketamine has been called the biggest thing to happen to psychiatry in 50 years, due to its uniquely rapid and sustained antidepressant effects. It improves symptoms in as little as 30 minutes, compared with weeks or even months for existing antidepressants, and is effective even for the roughly one third of patients with so-called …

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5 Myths About Depression That You Need To Hear

Depression is a condition that is poorly understood by the public. Major depressive disorder is widespread, one of the most prevalent mental health issues in this country. It affects an estimated 17.3 million residents including 8.7 percent of adult women and 5.3 percent of adult men. There is a stigmatism attached to depression that can keep …

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